Day 4- Pleural Effusions

When to do a thoracentesis:

  • aspiration should NOT be preformed for bilateral effusions in a clinical setting strongly suggestive of a transudate/heart failure

  • consider thoracentesis if:

    • suspect exudate

    • cause unclear

    • parapneumonic effusion (if <1cm of fluid on lateral decubitus in the context of pneumonia can forgo sampling and instead follow radiographically)

Exudate NYD:

  • can repeat thoracentesis once for increased sensitivity (sensitivity of pleural fluid cytology for malignancy increases to approx 80% with 2 thoracentesis)

  • CT chest

  • refer for pleural biopsy

JAMA: Does this patient have a pleural effusion? (EBM link)

  • Dullness to conventional percussion (+LR 10)

  • Asymmetric chest expansion (+LR 8.1)

  • Reduced vocal resonance (+LR 6.5)

  • Diminished breath sounds (+LR 4.3)

JAMA: Does this patient have an exudative pleural effusion? (EBM link)

  • Cholesterol level >55mg/dl (+LR 7.1-250)

  • Pleural LDH>200u/L (+LR 18)

  • Pleural: serum cholesterol ratio >0.3 (+LR 14)

JAMA Rational Clinical Exam

JAMA Rational Clinical Exam

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