Day 2- Anemia

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Iron Deficiency Anemia (CMAJ)

  • Most people with iron deficiency will need 150-200mg per day of elemental iron (2-5mg of iron per kg body weight per day)

    • Use ferrous fumarate, sulfate or gluconate once-daily or every-other-day dosing

    • Iron salts require an aciditc environment for absorption and should be taken on an empty stomach (with orange juice or vitamin C)

  • IV iron is indicated when: (Blood and Clots)

    • oral iron poorly tolerated or failure of oral trial

    • poor oral absorption (ie. gastritis)

    • rate of bleeding is too brisk for oral iron

    • severe anemia (Hb<90 g/L) especially if ongoing bleeding

    • time-sensitive pressures (ie. OR)

  • See transfusion blog post for indications for pRBC !

B12 Deficiency (CMAJ)

  • Vitamin B12 deficiency occurs frequently (>20%) among elderly people, but is often unrecognized

  • Causes include: food-cobalamin malabsorption syndrome (>60% of all cases), pernicious anemia, insufficiency dietary intake and malabsorption

  • 250-500 ug of vitamin B12 daily, consider IM injection if very low

NEJM Manifestations of Vitamin B12 Deficiency

NEJM Manifestations of Vitamin B12 Deficiency

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