Day 4 - Shock
Types of Shock
Distributive
Includes: Endocrine causes, sepsis, anaphylaxis
Look for SIRS/qSOFA criteria, infectious symptoms, mottled extremities/knees
Initial Treatment:
Early antibiotics
Fluid resuscitation
Vasopressors to keep MAP>65 if required
Norepinephrine is the first line vasopressor
Anaphylactic
Look for mucocutaneous edema, urticaria, respiratory distress, abdominal pain or nausea
Treatment:
Epinephrine IM (preferred over IV) dilution to 1:1000, administer 0.3-0.5mg, can repeat in 5-15min intervals
Adjunctive administration of H2 antihistamines (Ranitidine), and glucocorticoids
Endocrine
Adrenal Crisis
Look for hyponatremia, hyperkalemia, hypotension refractory to fluids, nausea, vomitting
Treatment: Hydrocortisone 100mg IV x 1 loading dose, then 50mg IV q6h
Myxedema Coma
Look for in patients with hypothyroidism, bradycardia, hypothermia, altered LOC
Treatment: IV levothyroxine + IV hydrocortisone
Hypovolemic
Look for signs of dehydration or hemorrhage
Treatment:
Fluid resuscitation
If bleeding - GIVE BLOOD
Treat underlying cause
Obstructive
Includes: Massive pulmonary embolism, tension pneumothorax, cardiac tamponade
Treat underlying cause
Cardiogenic
Look for evidence of coronary artery disease, acute myocardial infarction, cold extremities, pulmonary edema, arrhythmias (Bradycardia, unstable tachycardia)
Treatment:
Initial vasopressor is norepinephrine to target MAP 60-65
Initial inotrope is milrinone or dobutamine